Take for instance the work of Wes Anderson:
Though he may currently be the poster boy for symmetrical shots, I can think of very little instances in which the symmetry of the shot didn't add in some what to the content of the film. These kinds of shots don't take me out of the film, but rather draw me in to it's world and atmosphere. It's very rare that a serious drama would never design a shot that's as cloying twee as some of the examples posted above, but at the same time i don't think a lot of comedy films would benefit from the harsh lighting a lot of drama's benefit from.
It's all a matter of design really. If you feel that a shot would benefit from being arranged in a certain way, I really couldn't care less about what a book or professor might have to say.